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Usability & InteractionMember ingredient
Placebo Effect
Symptoms or reported outcomes can change through expectations and treatment context, but placebo effects vary and do not make an inactive intervention an effective substitute for care.
Public evidence overview
One checked source, with its limits.
This preview is not the complete evidence base. Use it as a question to investigate in your own product, not as a prediction of what an individual will do.
Checked source previewAcademic paper
Effects of Open-Label Placebos in Clinical Trials: A Systematic Review and Meta-Analysis
Research-assisted source review
- What it supports
- Open-label placebos showed a positive average effect, particularly on self-reported outcomes, but the evidence base was small and heterogeneous.
- Where it may not transfer
- High risk of bias, small studies, unblinded self-report, varying rationales and possible publication bias make the estimate uncertain. Evidence is insufficient for substitution for active care.
See how sources and limitations are checked in our editorial method.
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Practitioner includes the complete checked source set, study context and practical takeaways for this ingredient. The public overview above remains available without upgrading.